

A 2012 study found that adults with obesity who took bupropion SR (standard release) in 300mg or 400mg doses lost 7.2% and 10% of their body weight, respectively, over 24 weeks and maintained much of that weight loss at 48 weeks (Anderson, 2012). (This effect was not seen in smokers.) Users of the other antidepressants in the study gained weight (Arterburn, 2016).īupropion also seems to help with weight loss maintenance. Learn moreĪnother study from 2016 looked at the long-term weight loss effect of various antidepressants and found that non-smokers who took bupropion lost 7.1 pounds over two years.
#DEPRESSION ANXIETY WEIGHT LOSS PROFESSIONAL#
For the safe and proper use of Plenity, talk to a healthcare professional or refer to the Instructions for Use. Meet Plenity-an FDA‑cleared weight management tool But only one has been consistently associated with weight loss in studies: bupropion (brand name Wellbutrin).Ī 2019 meta-analysis of 27 studies on antidepressants and weight gain found that antidepressant use can increase body weight by an average of 5%-except bupropion, which was associated with weight loss (Alonso-Pedrero, 2019). There are more than a dozen antidepressant drugs that are popularly prescribed. Do some antidepressants cause weight loss? Here’s what the research says about how antidepressant use can affect what you see on the scale. If you’ve been prescribed an antidepressant, you may be curious about its potential effect on weight, particularly if it causes weight gain or weight loss. However, they are not a substitute for professional medical advice, diagnosis, or treatment. The articles on Health Guide are underpinned by peer-reviewed research and information drawn from medical societies and governmental agencies. If you have any medical questions or concerns, please talk to your healthcare provider.
